Kentucky Public Protection Secretary Bob Vance said he is retiring May 31.
Gov. Steve Beshear said his chief of staff, Larry Bond, will be the acting secretary until a permanent replacement is named.
Beshear appointed Vance after winning election in 2007. Vance worked in the banking industry in Kentucky, Ohio and Indiana.
The Public Protection Cabinet regulates banks, insurers and investment companies along with horse racing, alcohol sales and other industries. The state insurance regulatory office headed by Sharon P. Clark, insurance commissioner, falls under the Public Protection secretary.